Mutational analysis of Peroxiredoxin IV: exclusion of a positional candidate for multinodular goitre
Abstract Background Multinodular goitre (MNG) is a common disorder characterised by an enlargement of the thyroid, occurring as a compensatory response to hormonogenesis impairment.The incidence of MNG is dependent on sex (female:male ratio 5:1) and several reports have documented a genetic basis for the disease.Last year we mapped a MNG locus to c